![]() ![]() The “organization center” of the amphibian embryo: Its spatial organization and morphogenetic action. 179–220 In: Organizer: A Milestone of a Half Century from Spemann. Epigenetic formation of the organizer, p. Fates of the blastomeres of the 16-cell stage Xenopus embryo. Über die Inductionsfähigkeit der verschiedenen Bezirke der Neurula von Urodelen. Destruction of components of the neural induction system of the amphibian egg with ultraviolet irradiation. Expression of epi 1, an epidermal specific marker, in Xenopus laevis embryos is specified prior to gastrulation. In: Gastrulation: Movements, Patterns, and Molecules. Cell Motility, Control and Function of Convergence and Extension During Gastrulation in Xenopus. Regional expression, pattern and timing of convergence and extension during gastrulation of Xenopus laevis. The entire mesodermal mantle behaves as a Spemann’s organizer in dorsoanterior enhanced Xenopus laevis embryos. The association of neural inducing activity with the mesodermization of the trunk organizer. Studies on the formation and state of determination of the trunk organizer in the newt, Cynops pyrrhogaster. Tangential induction in the dorsal marginal zone. Studies of the formation and state of determination of the trunk organizer in the newt, Cynops pyrrhogaster. Spatial distribution of the capacity to initiate a secondary embryo in the 32-cell embryo of Xenopus laevis. Embryogenesis: Progressive differentiation. Region-specific neural induction of an engrailed protein by anterior notochord in Xenopus. The Heritage of Experimental Embryology, Hans Spemann and the Organizer. The amphibian grey crescent-a site of developmental information? Dev. Early cellular interactions promote embryonic axis formation in Xenopus laevis. Acquisition of developmental autonomy in the equatorial region of the Xenopus embryo. Region-specific cell activities in amphibian gastrulation. Cortical rotation of the Xenopus egg: Consequences for the anteropoasterior pattern of embryonic dorsal development. A transient array of parallel microtubules in frog eggs: Potential tracks for a cytoplasmic rotation that specifies the dorso-ventral axis. Two UV-sensitive targets in dorsoanterior specification in frog embryos. Patterning of the embryonic body axis during Xenopus gastrulation: The progressive anteriorization of cell fates. Cellular contacts required for neural induction in Xenopus embryos: Evidence for two signals. Patterning of the embryonic body axis during Xenopus gastrulation: Experimentally reduced morphogenesis leads to anteriorally truncated embryos. Regional specification within the mesoderm of early embryos of Xenopus laevis. Fate map of the 32 cell stage of Xenopus laevis. The Arrangement of Early Inductive Signals in Relation to Gastrulation Results from Frog and Chick, p. Suramin inhibition of growth factor receptor binding and mitogenicity in AKR-2B cells. The formation of the mesoderm in urodelian amphibians. So, the correct answer is 'Dorsal lip of the blastopore'.Beck, F. Hans Spemann and Hilde Mangold experiments proved that the dorsal lip of blastopore makes the neural tubes, cartilaginous skeletons, mesoderm etc and therefore called as the Specman's primary organizer. In embryology, an organizer is the morphogenetic effect caused by one organic tissue which produces a chemical molecule that affects another part of the embryo to form a part which otherwise would not have produced. The research by Hans Spemann (German embryologist) and his colleague Hilde Mangold did a transplantation experiment in frogs which led to the discovery of organizers. In the development of a frog embryo, the dorsal lip of the blastopore would be the spearman’s primary organizer. The newly formed zygote later goes through the mitotic divisions and forms a multicellular embryo. The embryogenesis starts with the fusion of the egg cell and sperm cell and gets fertilized, from which a zygote (diploid) is developed. Hint: The process of formation and development of an embryo is known as embryogenesis. ![]()
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